LYL1 and DRG1

Data Source:
HPRD (in vitro)

		LYL1	DRG1
Description		LYL1 basic helix-loop-helix family member	developmentally regulated GTP binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Cytosol Polysome Membrane Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	GTPase Activity Protein Binding GTP Binding Microtubule Binding Transcription Factor Binding Potassium Ion Binding Identical Protein Binding
	Biological Process	Blood Vessel Maturation Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Definitive Hemopoiesis	Cytoplasmic Translation Transcription, DNA-templated Multicellular Organism Development Positive Regulation Of Microtubule Polymerization Regulation Of Mitotic Spindle Assembly
Pathways		NGF-stimulated transcription
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Household income ( 31844048) Household income (MTAG) ( 31844048) Mean reticulocyte volume ( 32888494) Monocyte percentage of white cells ( 32888494) Plateletcrit ( 32888494) Refractive error ( 32231278)	Fish- and plant-related diet ( 32066663) Neutrophil count ( 32888494 27863252) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Sum basophil neutrophil counts ( 27863252) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		8 interacting genes: DRG1 LMO1 LMO2 NFKB1 NFKBIA RHOU TCF3 TCF4	16 interacting genes: CAPNS1 CLDN1 COIL LNX1 LYL1 MEOX2 PHC2 PTEN RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15
Entrez ID		4066	4733
HPRD ID		01046	16034
Ensembl ID		ENSG00000104903	ENSG00000185721
Uniprot IDs		P12980	Q9Y295
PDB IDs			2EKI
Enriched GO Terms of Interacting Partners?
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