CENPP and C2orf88

Data Source:
BioGRID (two hybrid)

		CENPP	C2orf88
Description		centromere protein P	chromosome 2 open reading frame 88
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol	Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	CENP-A Containing Nucleosome Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528)	Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		27 interacting genes: ATP6V0D2 BACH2 C2orf88 CCDC33 CCDC85B CENPO CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	11 interacting genes: ARMC7 BATF2 CENPP FBXO7 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2
Entrez ID		401541	84281
HPRD ID		17989	14436
Ensembl ID		ENSG00000188312	ENSG00000187699
Uniprot IDs		Q6IPU0 Q7Z672	Q9BSF0
PDB IDs			5HVZ
Enriched GO Terms of Interacting Partners?
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