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LMO2 and KRT34
Data Source:
BioGRID
(two hybrid)
LMO2
KRT34
Description
LIM domain only 2
keratin 34
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Transcription Regulator Complex
Extracellular Space
Cytosol
Intermediate Filament
Molecular Function
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coregulator Binding
Transcription Coactivator Activity
Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Structural Molecule Activity
Protein Binding
Biological Process
Multicellular Organism Development
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Epidermis Development
Keratinization
Cornification
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Keratinization
Formation of the cornified envelope
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Cognitive performance (
19734545
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Iron status biomarkers (transferrin saturation) (
28334935
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
188 interacting genes:
ABI2
ADAMTSL4
AFDN
AGTRAP
AIMP2
ALDH6A1
ARHGEF5
ARID5A
ARNT2
AXIN1
BANP
BCAS2
BEX2
BLZF1
BYSL
C1orf109
C1orf94
CALCOCO2
CBY2
CCDC33
CDC25A
CDC5L
CDX4
CLHC1
CMTM5
CORO1A
CORO1C
DAZAP2
DBF4B
DDIT3
DMRT3
DRAP1
DYDC1
EFHC1
EFHC2
EHMT2
EIF3B
EIF4EBP1
ELF2
ENKD1
ERBIN
FAAP20
FAM214B
FAM228A
FAM90A1
FHL3
FHL5
GAS8
GATA1
GATA2
GATA3
GFAP
GMEB2
GOLGA2
GRB2
HDAC5
HNRNPC
HNRNPM
HOOK1
ICA1L
IFT43
IHO1
IKZF1
IKZF3
INCA1
ISL1
ISY1
KANK2
KAZN
KDM5A
KIF2A
KIF3B
KPRP
KRT15
KRT34
KRT40
KRT75
KRT80
KRTAP10-7
LDB1
LDB2
LDOC1
LMO4
LMOD3
LYL1
LZTS1
LZTS2
MAGEA8
MAPRE1
MAPRE2
MAPRE3
MBIP
MISP
MRFAP1L1
MSN
MTUS2
MYOZ3
N4BP2L2
NCAPH2
NDOR1
NDUFAB1
NDUFB7
NFKBID
NHLH1
NIF3L1
NOTCH2NLA
NOXA1
NSMF
NTAQ1
NUP62
NUTM1
PATZ1
PAX9
PBX4
PDE9A
PHC2
POLR2G
PPP1R32
PRDM6
PRKG1
PSMA1
RBBP8
RCN1
REL
RELA
RINT1
RLIM
ROCK1
RTL8C
RUSC1
SAXO1
SGTB
SKP1
SMAD2
SMUG1
SNAPC5
SOX5
SP1
SSX2IP
STAT1
STAT3
STIP1
TAL1
TAL2
TBX2
TCP10L
TEKT3
TFIP11
TFPT
THAP6
TLE5
TLX3
TRIB3
TRIM23
TRIM54
TRIM55
TRIM63
TRIP6
TSC1
TSC22D4
TSEN15
TSEN54
TSGA10IP
TSPYL2
TSSK3
TUFT1
UBA6
UBASH3B
UBE2I
USH1G
VBP1
VEZF1
VMAC
WASF1
WASHC1
YOD1
YPEL3
ZFP64
ZMYND12
ZNF185
ZNF19
ZNF24
ZNF250
ZNF34
ZNF410
ZNF641
ZNF655
ZNF688
253 interacting genes:
A1CF
ABHD15
ABI2
ADRA2C
AGXT
AIMP2
ALDH3B1
AMOT
ANKRD11
ANKS1A
ARMC7
ASMTL
ATG9A
ATPAF2
BATF2
BCAS2
BEX1
BEX2
BEX3
BHLHE23
BOLA3
BRME1
C11orf87
C17orf50
C1orf216
C5orf49
CBX8
CCDC120
CCDC13
CCDC146
CCDC196
CCDC198
CCDC24
CCDC28A-AS1
CCHCR1
CCNC
CDC20B
CDK18
CERK
CFAP206
CFAP53
CHRD
CHRNG
CLCNKA
CLDN19
CLEC18A
CTRC
CWC25
CYSRT1
CYTH4
DCTN3
DDIT4L
DDX6
DHRS1
DMRT3
DOCK2
EFCAB3
EIF4G1
EPDR1
EXOC8
EXOSC5
FAM110A
FAM214B
FAM50B
FAM71C
FAM83A
FAM90A1
FARS2
FBXW5
FNDC11
FOXD4L1
FRS3
GADD45GIP1
GAST
GATAD2A
GEM
GLYCTK
GNE
GNG10
GNG13
GPS2
GRN
GSC2
GSTP1
HAPLN2
HBA1
HBA2
HCK
HDAC4
HGS
HOXA1
HOXB5
HOXB9
HOXC8
HSPA12B
HSPD1
HYAL2
ICAM4
INIP
INO80B
ISCU
ITGB5
ITPKB
JOSD1
KANK2
KCTD9
KDELR1
KIDINS220
KLC4
KLHL38
KLK8
KRT1
KRT20
KRT3
KRT6A
KRT6C
KRT71
KRT74
KRT75
KRT78
KRT79
KRT8
KRT80
KRT81
KRT82
KRT83
KRT85
KRT86
KRTAP12-2
KRTAP13-1
KRTAP19-5
KRTAP19-7
KRTAP26-1
LMO2
LMO4
LRRC29
LRRC41
LYSMD1
LYVE1
MAB21L2
MAD2L2
MAP3K7CL
MAPKBP1
MATR3
MBD3L2
METTL17
MIDN
MIIP
MKRN3
MNS1
MOS
MSRB3
MYO15B
MYOZ1
MYOZ3
NAB2
NAXD
NEK6
NFKBID
NMU
NOTO
NPBWR2
NUP42
P2RX7
PDE9A
PDGFRB
PGLYRP3
PIN1
PITX1
PITX2
PKN1
PLLP
POP5
PPP1R18
PPP1R27
PPP3R2
PRPF18
PRPF31
PRR19
PRR35
PSMA1
PSMB1
PTPMT1
R3HDM2
RAB33A
RAB3IL1
RASD1
RFC5
RIN1
RIPPLY1
RTP5
SAMD11
SCNM1
SEC14L4
SEMA4C
SHC3
SIRPA
SLC15A2
SLC22A5
SLC23A1
SLC25A42
SMARCD1
SMARCE1
SMCP
SMG9
SNRPB
SPAG8
SPATA46
SPRY3
STMN3
SUOX
TACO1
TAPBPL
TBC1D22B
TCHP
TEKT3
TEKT4
TENT5B
TEPSIN
TFAP2D
THAP7
TLE5
TLX3
TMEM174
TMIE
TMSB4X
TRARG1
TRIM42
TRIM73
TRIML2
TSG101
TTC23
TTC9C
TXLNA
TXLNB
USP2
UTP14C
UTP23
VENTX
WDR25
WWOX
ZDHHC1
ZFHX3
ZFYVE26
ZIC1
ZNF124
ZNF148
ZNF319
ZNF414
ZNF446
ZNF580
ZNF581
ZNF79
Entrez ID
4005
3885
HPRD ID
01586
04137
Ensembl ID
ENSG00000135363
ENSG00000131737
Uniprot IDs
P25791
O76011
PDB IDs
2XJY
2XJZ
2YPA
4KFZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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