ARHGDIB and RAC3

Data Source:
BioGRID (two hybrid)

		ARHGDIB	RAC3
Description		Rho GDP dissociation inhibitor beta	Rac family small GTPase 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane Cytoplasmic Vesicle Extracellular Exosome	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	GTPase Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Multicellular Organism Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Redox State Negative Regulation Of Trophoblast Cell Migration Regulation Of Actin Cytoskeleton Reorganization	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Wnt Signaling Pathway Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Rho GTPase cycle	Rho GTPase cycle PCP/CE pathway
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		13 interacting genes: ANKRD1 APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UBE3A UFM1 VAV1	10 interacting genes: ANKRD11 AR ARFIP2 ARHGDIA ARHGDIB CIB1 ESR1 HDAC7 HNF1A NRBP1
Entrez ID		397	5881
HPRD ID		04162	03629
Ensembl ID		ENSG00000111348	ENSG00000169750
Uniprot IDs		A0A024RAS5 P52566	P60763
PDB IDs		1DS6 5H1D	2C2H 2G0N 2IC5 2OV2 2QME 6TM1
Enriched GO Terms of Interacting Partners?
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