ARHGAP1 and BNIPL

Data Source:
HPRD (two hybrid, in vitro)

		ARHGAP1	BNIPL
Description		Rho GTPase activating protein 1	BCL2 interacting protein like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Sorting Endosome	Nucleus Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding Small GTPase Binding Cadherin Binding	Exopolyphosphatase Activity Protein Binding Identical Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Endosomal Transport Transferrin Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Endocytic Recycling	Polyphosphate Catabolic Process Apoptotic Process Negative Regulation Of Cell Population Proliferation Regulation Of Growth Rate
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Bone mineral density (hip) ( 19801982) Experiencing mood swings ( 29500382) Feeling miserable ( 29500382) Feeling nervous ( 29500382) Femoral neck bone mineral density ( 22504420) Neurociticism ( 29500382) Reaction time ( 29844566) Schizophrenia ( 29483656) Suffering from nerves ( 29500382)	Body mass index ( 26426971) Chronic kidney disease ( 20383146) Type 2 diabetes ( 30297969)
Interacting Genes		25 interacting genes: ADGRB2 AGTRAP BNIP2 BNIPL CDC42 CHEK2 EPB41L1 HMGCR HSP90AB1 ITPR1 KIF1B LINC01554 MTNR1B PIK3R1 PTPN11 RAC1 RASA1 RHOA RHOC SH3GL1 SMARCD3 SRC TAX1BP1 TUBA4A WAS	13 interacting genes: ARHGAP1 BCL2 BCL2L1 BNIP2 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 RHOU SNAPIN
Entrez ID		392	149428
HPRD ID		04108	16557
Ensembl ID		ENSG00000175220	ENSG00000163141
Uniprot IDs		Q07960	Q7Z465
PDB IDs		1AM4 1GRN 1OW3 1RGP 1TX4 2NGR 5M6X 5M70 6R3V
Enriched GO Terms of Interacting Partners?
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