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RHOG and ARHGDIG
Data Source:
HPRD
(two hybrid)
RHOG
ARHGDIG
Description
ras homolog family member G
Rho GDP dissociation inhibitor gamma
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Cell Cortex
Secretory Granule Membrane
Cytoplasmic Vesicle
Cell Projection
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Cytosol
Plasma Membrane
Membrane
Cytoplasmic Vesicle
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Protein Kinase Binding
Rho GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Actin Filament Organization
Establishment Or Maintenance Of Cell Polarity
Rho Protein Signal Transduction
Motor Neuron Axon Guidance
Positive Regulation Of Cell Population Proliferation
Regulation Of Cell Shape
Rac Protein Signal Transduction
Cell Projection Assembly
Actin Cytoskeleton Organization
Cortical Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Neutrophil Degranulation
Engulfment Of Apoptotic Cell
Positive Regulation Of Transcription, DNA-templated
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Kinase B Signaling
Cell Chemotaxis
Activation Of GTPase Activity
Regulation Of Ruffle Assembly
Regulation Of Neutrophil Migration
Positive Regulation Of Protein Localization To Plasma Membrane
Blastocyst Hatching
Negative Regulation Of Cell Adhesion
Rho Protein Signal Transduction
Regulation Of Protein Localization
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
GPVI-mediated activation cascade
PIP3 activates AKT signaling
Rho GTPase cycle
Constitutive Signaling by Aberrant PI3K in Cancer
RHO GTPases activate KTN1
Neutrophil degranulation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Rho GTPase cycle
Drugs
Diseases
GWAS
Lymphocyte percentage of white cells (
32888494
)
Malaria (
31844061
)
Plateletcrit (
32888494
)
Body mass index (
26426971
)
Interacting Genes
21 interacting genes:
ARHGDIA
ARHGDIG
CCR2
DOCK1
ECT2
ELMO1
ELMO2
ELMOD2
ERCC6
IQGAP2
KTN1
MAP3K11
MCF2
MCF2L
PLD1
SMAD1
SMAD4
TGFBR1
VAV1
VAV2
VAV3
12 interacting genes:
AGTR1
BICRAL
CDC42
CEP170P1
KXD1
MED10
RAC1
RHOA
RHOB
RHOG
RHOH
TACC3
Entrez ID
391
398
HPRD ID
01537
04163
Ensembl ID
ENSG00000177105
ENSG00000242173
Uniprot IDs
P84095
Q6ICQ8
F1T0H7
Q99819
PDB IDs
6UKA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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