SHISA6 and FBLIM1

Data Source:
BioGRID (two hybrid)

		SHISA6	FBLIM1
Description		shisa family member 6	filamin binding LIM protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Postsynaptic Density AMPA Glutamate Receptor Complex Dendritic Spine Membrane Postsynaptic Membrane Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Density Membrane	Fibrillar Center Stress Fiber Cytoplasm Cytosol Focal Adhesion Cell Junction Cell Periphery
	Molecular Function	Protein Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding	Protein Binding Filamin Binding Metal Ion Binding
	Biological Process	Spermatogenesis Wnt Signaling Pathway Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Postsynaptic Neurotransmitter Receptor Activity Postsynaptic Neurotransmitter Receptor Diffusion Trapping Excitatory Chemical Synaptic Transmission Regulation Of AMPA Glutamate Receptor Clustering Regulation Of AMPA Receptor Activity	Regulation Of Cell Shape Regulation Of Integrin Activation Cell Junction Assembly Cell-cell Adhesion
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Copper levels ( 26025379) Daytime sleep phenotypes ( 27126917) Myopia ( 27182965) Obesity-related traits ( 23251661) Refractive error ( 23396134 32231278) Seborrheic dermatitis ( 29203360) Sleep duration (short sleep) ( 30846698) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)	Alcoholic chronic pancreatitis ( 28754779) Cardiac Troponin-T levels ( 23247143) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549)
Interacting Genes		29 interacting genes: ANKS1A ARMC7 BAG3 CARD9 CCDC57 CDKN1A CIAO1 CTBP2 CYSRT1 EXOSC5 FBLIM1 GOLGA2 HSF2BP KAT5 KIF9 KIFC3 KRT31 KRTAP3-3 LMO3 NEDD4 OIP5 PFDN5 PLEKHG4 SMARCD1 TLE5 TRIP6 TSSK3 TTC19 UBASH3A	11 interacting genes: ADAT3 C19orf54 CUTA FERMT2 FLNA FLNB H3-5 H3C1 LMO3 SHISA6 TRIM15
Entrez ID		388336	54751
HPRD ID		13507	09669
Ensembl ID		ENSG00000188803	ENSG00000162458
Uniprot IDs		Q6ZSJ9	Q8WUP2
PDB IDs			2K9U 2W0P 4P3W
Enriched GO Terms of Interacting Partners?
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