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SUMO4 and STRAP
Data Source:
HPRD
(in vivo)
SUMO4
STRAP
Description
small ubiquitin like modifier 4
serine/threonine kinase receptor associated protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
SUMO Ligase Complex
Nucleus
Cytoplasm
Cytosol
SMN Complex
SMN-Sm Protein Complex
Molecular Function
Molecular_function
Protein Tag
Ubiquitin-like Protein Ligase Binding
RNA Binding
Signaling Receptor Binding
Protein Binding
Biological Process
Protein Sumoylation
Cellular Response To Oxidative Stress
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of DNA Binding
Negative Regulation Of DNA Binding
Negative Regulation Of Transcription, DNA-templated
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Spliceosomal SnRNP Assembly
Negative Regulation Of Epithelial Cell Migration
Negative Regulation Of Epithelial To Mesenchymal Transition
Maintenance Of Gastrointestinal Epithelium
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathways
Downregulation of TGF-beta receptor signaling
Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS
Dupuytren's disease (
28886342
)
Interacting Genes
75 interacting genes:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5F1B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RACK1
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
27 interacting genes:
CHEK2
GEMIN6
GEMIN7
MAP1B
MTRES1
NXF1
PBLD
PDPK1
PTEN
RN7SL1
RNU1-1
RNU2-1
SMAD2
SMAD3
SMAD6
SMAD7
SMN1
SMURF1
SNRPB
SNRPD2
SNRPD3
SNRPE
SUMO2
SUMO4
SZRD1
TGFBR1
TGFBR2
Entrez ID
387082
11171
HPRD ID
10584
05816
Ensembl ID
ENSG00000177688
ENSG00000023734
Uniprot IDs
Q6EEV6
B0AZV0
Q9Y3F4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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