KLRD1 and KLRC2

Data Source:
HPRD (in vivo)

		KLRD1	KLRC2
Description		killer cell lectin like receptor D1	killer cell lectin like receptor C2
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding MHC Class Ib Protein Binding, Via Antigen Binding Groove Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Activating MHC Class Ib Receptor Activity Protein Antigen Binding
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Cell Surface Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Cellular Defense Response Signal Transduction Positive Regulation Of Natural Killer Cell Degranulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling DAP12 signaling	DAP12 interactions DAP12 signaling DAP12 signaling
Drugs
Diseases
GWAS		Umami taste perception in obesity with metabolic syndrome ( 31005965)	Blood protein levels ( 28240269) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		6 interacting genes: HLA-B HLA-E HLA-G KLRC1 KLRC2 KLRC3	3 interacting genes: FBP1 HLA-E KLRD1
Entrez ID		3824	3822
HPRD ID		04204	04202
Ensembl ID		ENSG00000134539	ENSG00000205809
Uniprot IDs		Q13241 Q53ZY6	P26717
PDB IDs		1B6E 3BDW 3CDG 3CII	2L35
Enriched GO Terms of Interacting Partners?
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