KLRC1 and CD151

Data Source:
BioGRID (two hybrid)

		KLRC1	CD151
Description		killer cell lectin like receptor C1	CD151 molecule (Raph blood group)
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding	Integrin Binding Protein Binding
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Natural Killer Cell Inhibitory Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Cell Adhesion Viral Process Cell Migration Positive Regulation Of Cell Migration Hemidesmosome Assembly T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Drugs
Diseases			Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Blood protein levels ( 28240269) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Reticulocyte count ( 32888494)	Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		45 interacting genes: ATP6V0B ATP6V0C BMP10 BRICD5 C3orf52 CD151 CD82 CGRRF1 CLDN11 CLEC2D CLEC7A CLRN2 CTXN3 CXCL14 CYB561A3 EMP1 EMP3 ERMP1 GJB2 GJB4 GJB6 GPR61 HLA-E KLRD1 KLRG1 LSMEM2 MAL MALL MS4A13 NKG7 PLP1 PMP22 PTPN11 PTPN6 SFTPC TMEM182 TMEM262 TMEM54 TMPPE TSPO2 UNC93B1 UPK1B VAMP5 VTI1B ZFPL1	12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18
Entrez ID		3821	977
HPRD ID		01192	03763
Ensembl ID		ENSG00000134545	ENSG00000177697
Uniprot IDs		P26715	A0A024RCB3 P48509 Q6ZNZ0
PDB IDs		2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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