KCNH1 and ALG10

Data Source:
HPRD (in vitro)

		KCNH1	ALG10
Description		potassium voltage-gated channel subfamily H member 1	ALG10 alpha-1,2-glucosyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Axon Dendrite Early Endosome Membrane Presynaptic Membrane Perikaryon Intracellular Membrane-bounded Organelle Postsynaptic Density Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Cyclic Nucleotide Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity
	Biological Process	Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process
Pathways		Voltage gated Potassium channels	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Drugs		Enflurane Imipramine Astemizole Promethazine Miconazole
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Cholesterol ( 31902109) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379) Hematocrit ( 32888494) Hemoglobin ( 32888494)	Chronotype ( 30696823) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Methadone dose in opioid dependence ( 28115739) Morning person ( 30696823) Triglyceride levels ( 32203549)
Interacting Genes		10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP	8 interacting genes: CD79A ERGIC3 FBLN1 HERPUD2 KCNH1 KCNH2 SERP2 SHISAL1
Entrez ID		3756	84920
HPRD ID		04492	10346
Ensembl ID		ENSG00000143473	ENSG00000139133
Uniprot IDs		O95259	Q5BKT4
PDB IDs		5J7E
Enriched GO Terms of Interacting Partners?
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