PEAR1 and MXI1

Data Source:
BioGRID (two hybrid)

		PEAR1	MXI1
Description		platelet endothelial aggregation receptor 1	MAX interactor 1, dimerization protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Membrane Integral Component Of Membrane	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Signaling Receptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Phosphatidylinositol 3-kinase Signaling Protein Kinase B Signaling Recognition Of Apoptotic Cell Platelet Aggregation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Mean platelet volume ( 32888494 27863252) Platelet aggregation ( 20526338 29185836) Platelet count ( 29403010 32888494) Platelet distribution width ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Birth weight ( 31043758) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010 32888494) Normalized brain volume ( 19010793) Platelet count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010 32888494)
Interacting Genes		3 interacting genes: KRTAP4-5 MXI1 NUFIP2	28 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 USHBP1 ZNF655
Entrez ID		375033	4601
HPRD ID		18957	02486
Ensembl ID		ENSG00000187800	ENSG00000119950
Uniprot IDs		Q5VY43	A0A0S2Z3X5 P50539
PDB IDs
Enriched GO Terms of Interacting Partners?
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