ITGB5 and STAB2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		ITGB5	STAB2
Description		integrin subunit beta 5	stabilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Exosome	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endocytic Vesicle Membrane
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Protein Disulfide Oxidoreductase Activity Low-density Lipoprotein Particle Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Muscle Contraction Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Stress Fiber Assembly Viral Entry Into Host Cell Epithelial Cell-cell Adhesion	Angiogenesis Endocytosis Receptor-mediated Endocytosis Cell Adhesion Hyaluronan Catabolic Process Defense Response To Bacterium Defense Response To Gram-positive Bacterium
Pathways		Cross-presentation of particulate exogenous antigens (phagosomes) Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Syndecan interactions Syndecan interactions ECM proteoglycans Smooth Muscle Contraction	Hyaluronan uptake and degradation Scavenging by Class H Receptors
Drugs			Hyaluronic acid
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Carpal tunnel syndrome ( 30833571) Coronary artery disease ( 28714974) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin concentration ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)	Adverse response to drug ( 30420678) Coronary restenosis ( 21878436) Daytime sleep phenotypes ( 27126917) Factor VIII levels ( 30586737) Low vWF levels ( 26486471) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Sense of smell ( 26632684) Stem cell growth factor beta levels ( 27989323) vWF and FVIII levels ( 21810271) vWF levels ( 20231535 30586737)
Interacting Genes		58 interacting genes: ANXA5 APPBP2 CCN1 CYSRT1 DAB1 DAB2 DOK1 EFEMP2 EHMT2 EPS8 EWSR1 FDFT1 FHL2 FHL3 FLNA GAPDH GOLGA2 GON4L ITGA5 ITGAV ITGB3BP KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP5-7 LTBP1 LTBP3 MTDH MTUS2 MYBPC2 MYO10 NBPF19 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TAF1 TLN1 TNS2 TRIM55 TRIM63 TTN ZBTB17 ZNF655	1 interacting genes: ITGB5
Entrez ID		3693	55576
HPRD ID		00949	10542
Ensembl ID		ENSG00000082781	ENSG00000136011
Uniprot IDs		D3DNA1 L7RT22 P18084	Q8WWQ8
PDB IDs			5N86
Enriched GO Terms of Interacting Partners?
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