ITGA3 and HPS5

Data Source:
HPRD (two hybrid)

		ITGA3	HPS5
Description		integrin subunit alpha 3	HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Cell Periphery Synaptic Membrane Growth Cone Filopodium	Cytosol BLOC-2 Complex
	Molecular Function	Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Memory Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Extracellular Matrix Organization Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Response To Drug Skin Development Mesodermal Cell Differentiation Leukocyte Migration Maternal Process Involved In Female Pregnancy Nephron Development Dendritic Spine Maintenance Renal Filtration Positive Regulation Of Protein Localization To Plasma Membrane	Organelle Organization Blood Coagulation Pigmentation
Pathways		Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling
Drugs
Diseases			Hermansky-Pudlak syndrome (HPS)
GWAS			Amyloid A serum levels ( 21124955) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Metabolic traits ( 21886157) Serum metabolite levels ( 23093944) Survival in pancreatic cancer ( 28470677) Triglyceride levels ( 32203549)
Interacting Genes		15 interacting genes: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4	2 interacting genes: HPS6 ITGA3
Entrez ID		3675	11234
HPRD ID		05431	07395
Ensembl ID		ENSG00000005884	ENSG00000110756
Uniprot IDs		A0A140VJM0 P26006	Q9UPZ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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