IMPA1 and S100B

Data Source:
BioGRID (pull down, imaging technique, enzymatic study)

		IMPA1	S100B
Description		inositol monophosphatase 1	S100 calcium binding protein B
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation	Axonogenesis Central Nervous System Development Learning Or Memory Positive Regulation Of Cell Population Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Lithium cation L-Myo-Inositol-1-Phosphate Lithium citrate Lithium succinate Lithium carbonate	Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Ovarian cancer ( 23535730)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)
Interacting Genes		4 interacting genes: CALB1 IMPA2 NXF1 S100B	46 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1
Entrez ID		3612	6285
HPRD ID		03641	01505
Ensembl ID		ENSG00000133731	ENSG00000160307
Uniprot IDs		A0A024R830 A0A140VJL8 P29218	A0A0S2Z4C5 P04271
PDB IDs		1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4 6GIU 6GJ0 6ZK0	1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?