KRTAP12-2 and SLC12A4

Data Source:
BioGRID (two hybrid)

		KRTAP12-2	SLC12A4
Description		keratin associated protein 12-2	solute carrier family 12 member 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Synapse
	Molecular Function	Protein Binding	Protein Binding Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding
	Biological Process	Keratinization	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Keratinization	Cation-coupled Chloride cotransporters
Drugs			Potassium chloride Bumetanide
Diseases
GWAS			Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		125 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1C LCE1F LCE2A LCE2B LCE4A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPRED2 SPRY1 SRSF8 TCEA2 TEX37 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1	10 interacting genes: AP3M1 ATF7IP CNFN CYSRT1 KRTAP12-2 KRTAP19-2 MB21D2 MTNR1B TMEM102 ZNF655
Entrez ID		353323	6560
HPRD ID		11198	04987
Ensembl ID		ENSG00000221864	ENSG00000124067
Uniprot IDs		P59991	B4DF30 Q9UP95
PDB IDs			6KKR 6KKT 6KKU
Enriched GO Terms of Interacting Partners?
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