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IGFALS and PDCD6
Data Source:
HPRD
(in vivo)
IGFALS
PDCD6
Description
insulin like growth factor binding protein acid labile subunit
programmed cell death 6
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Matrix
Insulin-like Growth Factor Ternary Complex
Extracellular Exosome
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
COPII Vesicle Coat
Cytoplasmic Vesicle
Cul3-RING Ubiquitin Ligase Complex
Extracellular Exosome
Endoplasmic Reticulum Exit Site
Molecular Function
Insulin-like Growth Factor Binding
Magnesium Ion Binding
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Protein Homodimerization Activity
Protein-membrane Adaptor Activity
Protein Dimerization Activity
Calcium-dependent Protein Binding
Ubiquitin Ligase-substrate Adaptor Activity
Biological Process
Cell Adhesion
Signal Transduction
Cellular Protein Metabolic Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Neural Crest Formation
Neural Crest Cell Development
Protein Ubiquitination
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
COPII Vesicle Coating
Response To Calcium Ion
Negative Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Positive Regulation Of Protein Monoubiquitination
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Zinc
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Calcium
Zinc
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Zinc acetate
Diseases
GWAS
Blood protein levels (
30072576
)
Insulin-like growth factors (
21216879
)
Mean corpuscular hemoglobin (
32888494
)
Interacting Genes
4 interacting genes:
IGF1
IGFBP3
IGFBP5
PDCD6
22 interacting genes:
ANXA11
ANXA7
BAG4
CDKN2A
CPNE1
CPNE2
CPNE4
CUL3
FAS
FASLG
HEBP2
IGFALS
MAP3K5
MAPK1IP1L
PDCD6IP
PEF1
PRR19
SEC31A
SH3KBP1
TIMM22
VPS37C
YWHAQ
Entrez ID
3483
10016
HPRD ID
03290
03035
Ensembl ID
ENSG00000099769
ENSG00000249915
Uniprot IDs
P35858
Q8TAY0
A0A024QZ42
A0A087WZ38
O75340
Q53FC3
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
3WXA
5GQQ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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