SERINC2 and CCDC167

Data Source:
BioGRID (two hybrid)

		SERINC2	CCDC167
Description		serine incorporator 2	coiled-coil domain containing 167
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Extracellular Exosome	Integral Component Of Membrane
	Molecular Function		Protein Binding
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity
Pathways		Serine biosynthesis
Drugs
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Acne (severe) ( 24927181) Restless legs syndrome ( 29029846) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		16 interacting genes: C4orf3 CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B	42 interacting genes: APPBP2 AQP2 AQP6 AQP9 ARL13B CD79A CLDN5 CX3CR1 EBP ELOVL4 ERGIC3 FAM174A FAM210B FFAR2 GJA8 GLP1R GOLT1A GPR152 GPR42 HSD17B13 MS4A3 MTNR1A MUC1 NIPA1 OPRM1 RETREG3 SERINC2 SLC10A6 SLC18A3 SLC35C2 SLC7A14 SYT2 TACR1 TLCD4 TM4SF19 TMEM179B TMEM237 TMEM51 TMEM80 TMEM86B TMX2 VKORC1
Entrez ID		347735	154467
HPRD ID		15481	18561
Ensembl ID		ENSG00000168528	ENSG00000198937
Uniprot IDs		Q96IM8 Q96SA4	Q9P0B6
PDB IDs
Enriched GO Terms of Interacting Partners?
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