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APOD and FPR2
Data Source:
BioGRID
(two hybrid)
APOD
FPR2
Description
apolipoprotein D
formyl peptide receptor 2
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Cytosolic Ribosome
Dendrite
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cytoplasm
Plasma Membrane
Integral Component Of Membrane
Specific Granule Membrane
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
Lipid Transporter Activity
Protein Binding
Cholesterol Binding
Amyloid-beta Binding
Complement Receptor Activity
G Protein-coupled Receptor Activity
N-formyl Peptide Receptor Activity
Scavenger Receptor Binding
Protein Binding
Signaling Receptor Activity
Cargo Receptor Activity
Biological Process
Response To Reactive Oxygen Species
Angiogenesis
Glucose Metabolic Process
Lipid Metabolic Process
Lipid Transport
Brain Development
Aging
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Peripheral Nervous System Axon Regeneration
Tissue Regeneration
Negative Regulation Of Protein Import Into Nucleus
Response To Drug
Negative Regulation Of Smooth Muscle Cell Proliferation
Response To Axon Injury
Negative Regulation Of Focal Adhesion Assembly
Negative Regulation Of Lipoprotein Lipid Oxidation
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Smooth Muscle Cell-matrix Adhesion
Negative Regulation Of T Cell Migration
Microglial Cell Activation
Positive Regulation Of Protein Phosphorylation
Complement Receptor Mediated Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Receptor-mediated Endocytosis
Chemotaxis
Inflammatory Response
Cell Adhesion
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Positive Regulation Of Superoxide Anion Generation
Defense Response To Bacterium
Neutrophil Degranulation
Positive Regulation Of Innate Immune Response
Astrocyte Activation
Negative Regulation Of Inflammatory Response
Positive Regulation Of Phagocytosis
Positive Chemotaxis
Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Monocyte Chemotaxis
Cellular Response To Amyloid-beta
Pathways
Transport of fatty acids
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
Neutrophil degranulation
Drugs
Vitamin A
Copper
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Alopecia areata (
25608926
)
Multiple sclerosis (
31604244
24076602
)
Tourette syndrome (
30818990
)
Interacting Genes
51 interacting genes:
AIG1
APH1A
APOA2
AQP9
ATP6V0B
ATP6V0E1
BCL2L13
BIK
CD53
CD79A
CLDN7
CLEC10A
CPLX4
CREB3
CREB3L1
ERGIC3
EVI2B
FAM209A
FFAR2
FKBP7
FPR2
GDAP1
GJA8
GORAB
GPR151
GPR42
GPX8
KCNJ6
KIR2DL3
LEPR
LMNA
MFF
MGST3
MTERF2
MTIF3
NCAPH2
PDZK1IP1
POLR2M
RHBDL1
SHBG
SIGLECL1
SLC10A6
SLC35C2
TEX29
TMEM237
TMEM31
TMEM45B
TMEM52B
TMEM79
VAPA
VSIR
5 interacting genes:
APOD
CAMP
FXYD6
LRRC25
SSMEM1
Entrez ID
347
2358
HPRD ID
00134
00647
Ensembl ID
ENSG00000189058
ENSG00000171049
Uniprot IDs
P05090
A0A024R4P3
P25090
PDB IDs
2APD
2HZQ
2HZR
6LW5
6OMM
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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