RSPO4 and GUCD1

Data Source:
BioGRID (two hybrid)

		RSPO4	GUCD1
Description		R-spondin 4	guanylyl cyclase domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Protein Binding Heparin Binding	Protein Binding
	Biological Process	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development
Pathways		Regulation of FZD by ubiquitination
Drugs
Diseases		Anonychia congenita
GWAS		Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)	Acne (severe) ( 24927181)
Interacting Genes		15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77	77 interacting genes: ADAM12 ADAMTSL4 APP ATP23 BEGAIN CCDC153 CPSF7 CRX CTAG1A CTAG1B CTH CYSRT1 FCHO1 FHL3 FUCA2 HESX1 HOXA1 HSPB7 ID3 ISCA2 KATNBL1 KPRP KRT40 KRTAP1-1 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP19-5 KRTAP19-6 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP5-7 KRTAP9-2 KRTAP9-8 LASP1 LCE1C LCE2A LCE2B LCE2D LHX3 LNX1 MAP2K5 MEOX2 MORN3 MORN4 NDUFAF6 NGLY1 PCBD2 PCSK5 PFDN5 PSMA1 PTH1R RSPO4 RUNX3 SLC25A48 SMCP SPRY1 SYNGAP1 TCF4 TEPSIN TFAP2D TOLLIP TRIM42 TSPAN4 TXN2 VASN YPEL3 ZBTB42 ZCCHC13 ZNF250 ZNF655 ZNF705D ZNF835
Entrez ID		343637	83606
HPRD ID		18788	12796
Ensembl ID		ENSG00000101282	ENSG00000138867
Uniprot IDs		Q2I0M5	A0A024R1B8 A0A087WVD9 B4DL90 E7EX77 E9PGZ7 Q7Z629 Q96NT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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