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KRTAP11-1 and PLA2G10
Data Source:
BioGRID
(two hybrid)
KRTAP11-1
PLA2G10
Description
keratin associated protein 11-1
phospholipase A2 group X
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Intermediate Filament
Acrosomal Vesicle
Extracellular Region
Extracellular Space
Lysosome
Molecular Function
Protein Binding
1-alkyl-2-acetylglycerophosphocholine Esterase Activity
Phospholipase Activity
Phospholipase A2 Activity
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipase A2 Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
Keratinization
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Phosphatidylserine Metabolic Process
Axon Guidance
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Lipid Storage
Arachidonic Acid Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Prostaglandin Secretion
Low-density Lipoprotein Particle Remodeling
Phosphatidylcholine Catabolic Process
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylinositol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Phosphatidylethanolamine Acyl-chain Remodeling
Cholesterol Homeostasis
Regulation Of Macrophage Activation
Negative Regulation Of DNA-binding Transcription Factor Activity
Phosphatidylethanolamine Metabolic Process
Phosphatidylcholine Metabolic Process
Phosphatidylglycerol Metabolic Process
Phosphatidic Acid Metabolic Process
Arachidonic Acid Secretion
Defense Response To Virus
Lysophospholipid Transport
Platelet Activating Factor Catabolic Process
Positive Regulation Of Arachidonic Acid Secretion
Negative Regulation Of Cholesterol Efflux
Positive Regulation Of Acrosome Reaction
Pathways
Keratinization
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA
Drugs
Varespladib methyl
Crotalus adamanteus antivenin
Agkistrodon piscivorus antivenin
Diseases
GWAS
Height (
28552196
)
Cholesteryl ester levels (
31551469
)
Glycerophospholipid levels (
26068415
)
Interacting Genes
104 interacting genes:
AGR3
ANAPC11
ANKS1A
ASB13
ATG9A
ATXN1L
BEX2
CERK
CFP
CHERP
CRYBA1
CRYBA2
CSKMT
CYSRT1
DHRS1
DTX2
DUSP21
EFEMP2
ENKD1
ETFDH
FAM222B
FANCL
FASLG
FBLN1
FNDC3B
FOXH1
FRS3
GATA2
GNE
GPS2
GPSM3
GRN
HEY2
HOXA1
HOXC8
HR
KLHL38
KRT83
KRTAP10-5
KRTAP10-8
KRTAP12-1
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP15-1
KRTAP26-1
KRTAP4-11
KRTAP4-2
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1F
LCE2A
LCE3A
LCE3C
LGALS4
LIMS3
LIMS4
LMO4
MEIS2
MICOS10-NBL1
NBL1
NUFIP2
OIT3
OLIG3
OR7A17
OTX1
PCSK5
PLA2G10
PLSCR3
RBPMS
RBPMS2
RNF38
SLC13A5
SNRPC
SPAG8
SPRY1
STK16
TBX6
TEKT4
TENT5D
TFAP2D
TLE5
TLX3
TNS2
TRIM54
VASN
VENTX
VGLL3
VWC2L
WWOX
YIPF3
ZDHHC17
ZIC1
49 interacting genes:
AGXT
AQP1
ARID5A
ATXN1
BAG3
BEX2
C1orf94
CATSPER1
CCDC120
CREB5
CYSRT1
FAM222B
FOXH1
GATA5
GNE
HGS
HOXC8
HR
HSF4
INCA1
KPRP
KRTAP11-1
KRTAP26-1
LCE1A
LCE1C
LCE2A
LCE2B
LCE2D
MAL
MAPKBP1
MGAT5B
MYO10
NOXA1
NTAQ1
OTX1
PITX1
PLA2R1
POU4F3
PPP1R32
ROR2
SNRPC
SPAG8
STK16
TBX6
TFG
TLX3
VGLL3
VPS37C
ZC3H10
Entrez ID
337880
8399
HPRD ID
11196
04674
Ensembl ID
ENSG00000182591
ENSG00000069764
Uniprot IDs
Q8IUC1
O15496
PDB IDs
1LE6
1LE7
4UY1
5G3M
5OW8
5OWC
6G5J
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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