HTR3A and CANX

Data Source:
HPRD (in vitro, in vivo)

		HTR3A	CANX
Description		5-hydroxytryptamine receptor 3A	calnexin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Cleavage Furrow Neuron Projection Neuronal Cell Body Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane Serotonin-activated Cation-selective Channel Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Melanosome Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Presynapse
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Serotonin-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Serotonin Binding	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Unfolded Protein Binding
	Biological Process	Signal Transduction Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Ion Transmembrane Transporter Activity Ion Transmembrane Transport Response To Cocaine Regulation Of Membrane Potential Response To Ethanol Nervous System Process Cellular Response To Growth Factor Stimulus	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Folding Protein Secretion Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Interleukin-27-mediated Signaling Pathway Interleukin-35-mediated Signaling Pathway Clathrin-dependent Endocytosis
Pathways		Neurotransmitter receptors and postsynaptic signal transmission	Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Ziprasidone Methadone Olanzapine Clozapine Palonosetron Loxapine Amoxapine Lamotrigine Cisapride Paroxetine Procaine Trimipramine Rocuronium Dolasetron Granisetron Ethanol Ondansetron Alosetron Dopamine Memantine Ergoloid mesylate Bupropion Tubocurarine Ketamine Quetiapine Metoclopramide Aripiprazole Chlorprothixene Cilansetron Renzapride DDP733 DDP-225 Tapentadol Ticalopride Serotonin Cannabidiol Vortioxetine Ramosetron Setiptiline Dihydroergocornine Tropisetron Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil	Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate
Diseases
GWAS		Chronic kidney disease ( 26420894) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 31604244)	Daytime sleep phenotypes ( 27126917) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 32888494 27863252)
Interacting Genes		2 interacting genes: CANX HSPA5	47 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR
Entrez ID		3359	821
HPRD ID		08917	00252
Ensembl ID		ENSG00000166736	ENSG00000127022
Uniprot IDs		B4E398 P46098	P27824
PDB IDs
Enriched GO Terms of Interacting Partners?
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