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HSPA8 and LINC01554
Data Source:
BioGRID
(unspecified method)
HSPA8
LINC01554
Description
heat shock protein family A (Hsp70) member 8
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Prp19 Complex
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Cytoplasm
Lysosome
Lysosomal Membrane
Late Endosome
Autophagosome
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Dendrite
Secretory Granule Lumen
Melanosome
Terminal Bouton
Lysosomal Lumen
Perinuclear Region Of Cytoplasm
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Extracellular Exosome
Blood Microparticle
Lumenal Side Of Lysosomal Membrane
Photoreceptor Ribbon Synapse
Glycinergic Synapse
Glutamatergic Synapse
Presynaptic Cytosol
Postsynaptic Cytosol
Postsynaptic Specialization Membrane
Chaperone Complex
Ficolin-1-rich Granule Lumen
Ribonucleoprotein Complex
Molecular Function
G Protein-coupled Receptor Binding
Phosphatidylserine Binding
RNA Binding
Protein Binding
ATP Binding
ATPase Activity
Enzyme Binding
MHC Class II Protein Complex Binding
Protein-macromolecule Adaptor Activity
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein Folding Chaperone
Cadherin Binding
Unfolded Protein Binding
Chaperone Binding
Misfolded Protein Binding
C3HC4-type RING Finger Domain Binding
Clathrin-uncoating ATPase Activity
Biological Process
MRNA Splicing, Via Spliceosome
Protein Folding
Response To Unfolded Protein
Neurotransmitter Secretion
Cellular Response To Starvation
Viral Process
Vesicle-mediated Transport
Cytokine-mediated Signaling Pathway
Regulation Of Protein Stability
Cellular Response To Unfolded Protein
Protein Refolding
Regulation Of Protein-containing Complex Assembly
Neutrophil Degranulation
Regulation Of MRNA Stability
Positive Regulation By Host Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
ATP Metabolic Process
Positive Regulation Of MRNA Splicing, Via Spliceosome
Chaperone Cofactor-dependent Protein Refolding
Regulation Of Cell Cycle
Membrane Organization
Regulation Of Protein Complex Stability
Chaperone-mediated Autophagy
Late Endosomal Microautophagy
Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy
Chaperone-mediated Protein Transport Involved In Chaperone-mediated Autophagy
Clathrin Coat Disassembly
Regulation Of Postsynapse Organization
Regulation Of Cellular Response To Heat
Negative Regulation Of Supramolecular Fiber Organization
Regulation Of Protein Import
Chaperone-mediated Autophagy Translocation Complex Disassembly
Slow Axonal Transport
Pathways
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Attenuation phase
HSF1-dependent transactivation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
CHL1 interactions
AUF1 (hnRNP D0) binds and destabilizes mRNA
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
mRNA Splicing - Major Pathway
Clathrin-mediated endocytosis
Protein methylation
GABA synthesis, release, reuptake and degradation
Lipophagy
Chaperone Mediated Autophagy
Late endosomal microautophagy
Drugs
Dasatinib
(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Copper
Artenimol
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
29403010
32888494
)
Postoperative acute renal failure after cardiac surgery (
30678657
)
Red cell distribution width (
32888494
)
Interacting Genes
91 interacting genes:
ABI1
AIPL1
ALDOB
APOB
ATM
BAG1
BAG2
BAG3
BAG4
BAG6
BRCA1
CAPZA1
CAPZB
CCT3
CD40
CDKN2A
CITED1
CLTA
COL7A1
CXCR4
CYCS
DNAJA1
DNAJA3
DNAJB1
DPP3
DYNLL1
EGFR
ENO1
ERBB3
ERH
ESR1
FANCC
FBP1
GAK
GCH1
GOT2
H3C1
HDAC10
HDAC3
HGS
HLTF
HSF1
HSP90AA1
HSPA1A
HSPBP1
HSPH1
HTN3
HTT
IL32
JAK2
JUN
LALBA
LINC01554
MAPK8
MAPT
METTL21A
NMI
NOA1
PHC1
PPID
PTEN
PTPRF
RAF1
RB1
REL
RGS2
SGTA
SIRPA
SP1
SRRT
ST13
STAT1
STIP1
STMN1
STUB1
SUMO2
SUMO4
TADA3
TCAP
TCERG1
TGM2
TM4SF1
TNFRSF1A
TRIM38
TSSK6
TTC1
UBC
UCHL1
VHL
YWHAG
YWHAQ
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
3312
202299
HPRD ID
07205
16896
Ensembl ID
ENSG00000109971
ENSG00000236882
Uniprot IDs
P11142
Q53HF2
V9HW22
PDB IDs
3AGY
3AGZ
3ESK
3FZF
3FZH
3FZK
3FZL
3FZM
3LDQ
3M3Z
4H5N
4H5R
4H5T
4H5V
4H5W
4HWI
4KBQ
5AQF
5AQG
5AQH
5AQI
5AQJ
5AQK
5AQL
5AQM
5AQN
5AQO
5AQP
5AQQ
5AQR
5AQS
5AQT
5AQU
5AQV
6B1I
6B1M
6B1N
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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