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HOXB9 and TAL1
Data Source:
BioGRID
(two hybrid)
HOXB9
TAL1
Description
homeobox B9
TAL bHLH transcription factor 1, erythroid differentiation factor
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
RNA Polymerase II Transcription Regulator Complex
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Lsd1/2 Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Enzyme Binding
Histone Deacetylase Binding
Protein Dimerization Activity
E-box Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Anterior/posterior Pattern Specification
Proximal/distal Pattern Formation
Mammary Gland Development
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Skeletal System Morphogenesis
Cell Chemotaxis
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Locomotory Behavior
Spinal Cord Association Neuron Differentiation
Hemopoiesis
Erythrocyte Differentiation
Megakaryocyte Differentiation
Platelet Formation
Basophil Differentiation
Positive Regulation Of Protein-containing Complex Assembly
Embryonic Hemopoiesis
Megakaryocyte Development
Regulation Of Cell Population Proliferation
Erythrocyte Maturation
Cell Fate Commitment
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Chromatin Assembly Or Disassembly
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Division
Astrocyte Fate Commitment
Definitive Hemopoiesis
Hemangioblast Cell Differentiation
Hematopoietic Stem Cell Differentiation
Regulation Of Mast Cell Differentiation
Positive Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Hematopoietic Stem Cell Differentiation
Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Signaling Receptor Activity
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Transcriptional regulation of granulopoiesis
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Celiac disease (
24999842
)
Adult body size (
32376654
)
Body mass index (
25673413
)
Clozapine-induced agranulocytosis (
25187353
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
)
Interacting Genes
67 interacting genes:
BPIFA1
BTG1
BTG2
CALCOCO2
CARD10
CREBBP
CYSRT1
EP300
EXOSC8
FAM168B
FHL5
GOLGA2
GOLGA6L9
HOPX
HOXA1
HSPB2
HSPB2-C11orf52
ING4
KAT2B
KRT27
KRT34
KRT40
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP17-1
KRTAP19-5
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
LZTS2
MDFI
MID2
MTUS2
MYBBP1A
NBPF19
NOTCH2NLA
OIP5
PCSK5
PFDN5
PHTF1
PLEKHG4
PNMA1
POLR1C
RBPMS
SAT1
SFMBT1
SIRT1
SOX15
SPZ1
TAL1
TENM4
TET2
TNS2
TRIM27
TRIP6
ZNF408
23 interacting genes:
CHD3
DRG1
ELSPBP1
EP300
GATA1
GATA2
GATA3
HDAC1
HOXB9
KAT2B
KDM1A
LMO1
LMO2
MAPK3
NCAPG2
PRKCQ
SIN3A
SKP2
SP1
STUB1
TCF3
TCF4
ZHX1
Entrez ID
3219
6886
HPRD ID
00852
01753
Ensembl ID
ENSG00000170689
ENSG00000162367
Uniprot IDs
B3KPJ1
P17482
P17542
Q16509
PDB IDs
2YPA
2YPB
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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