HOXB8 and PBX3

Data Source:
HPRD (in vivo)

		HOXB8	PBX3
Description		homeobox B8	PBX homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Grooming Behavior Adult Locomotory Behavior Anterior/posterior Pattern Specification Sensory Perception Of Pain Dorsal Spinal Cord Development Negative Regulation Of Myeloid Cell Differentiation Embryonic Skeletal System Morphogenesis	Eye Development Regulation Of Transcription By RNA Polymerase II Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Animal Organ Morphogenesis Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS			Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		4 interacting genes: MEIS1 PBX1 PBX2 PBX3	63 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3
Entrez ID		3218	5090
HPRD ID		00851	15938
Ensembl ID		ENSG00000120068	ENSG00000167081
Uniprot IDs		I3L3R1 P17481 Q8N8T3	P40426 Q5JS98 Q96AL5
PDB IDs
Enriched GO Terms of Interacting Partners?
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