HOXA13 and MEIS2

Data Source:
HPRD (two hybrid)

		HOXA13	MEIS2
Description		homeobox A13	Meis homeobox 2
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Chromosome Intermediate Filament Cytoskeleton	Chromatin Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Skeletal System Development Vasculogenesis Endothelial Cell Morphogenesis Tissue Homeostasis Ventricular Septum Development Regulation Of Transcription By RNA Polymerase II Regulation Of BMP Signaling Pathway Male Genitalia Development Embryonic Forelimb Morphogenesis Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Inner Ear Development Artery Morphogenesis Branching Involved In Prostate Gland Morphogenesis Endothelial Cell Fate Specification Positive Regulation Of Mesenchymal Cell Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs
Diseases		Hand-foot-genital syndrome Guttmacher syndrome
GWAS		Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729) Metabolite levels ( 23823483)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		6 interacting genes: MEIS1 MEIS2 MEIS3 SMAD1 SMAD2 SMAD5	49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3
Entrez ID		3209	4212
HPRD ID		00847	03443
Ensembl ID		ENSG00000106031	ENSG00000134138
Uniprot IDs		P31271 Q6DI00	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs		2L7Z	3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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