TLX1 and PKNOX1

Data Source:
HPRD (in vitro)

		TLX1	PKNOX1
Description		T cell leukemia homeobox 1	PBX/knotted 1 homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development	Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)	Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)
Interacting Genes		8 interacting genes: MEIS1 NFIC PKNOX1 PPP1CB PPP1CC PPP2CA PPP2CB TLE1	23 interacting genes: APP BLOC1S5 BORCS6 FAM110B FHL2 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 MPP3 NUP58 PAX6 PBX1 PBX2 PBX4 POU2F1 RFX3 TET2 TLX1 VPS37C ZBTB3
Entrez ID		3195	5316
HPRD ID		01728	03653
Ensembl ID		ENSG00000107807	ENSG00000160199
Uniprot IDs		P31314	B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87
PDB IDs			1X2N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?