HNRNPL and MIR205

Data Source:
BioGRID (unspecified method)

		HNRNPL	MIR205
Description		heterogeneous nuclear ribonucleoprotein L	microRNA 205
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Extracellular Space
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Intronic Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing RNA Metabolic Process Regulation Of RNA Splicing	Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Metalloendopeptidase Activity
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		89 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PCBP2 PJA1 PTBP1 SUMO2 SUMO4	92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346
Entrez ID		3191	406988
HPRD ID		04360
Ensembl ID		ENSG00000104824	ENSG00000284485
Uniprot IDs		P14866 Q6NTA2
PDB IDs		3R27 3TO8
Enriched GO Terms of Interacting Partners?
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