HNRNPH1 and KHSRP

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HNRNPH1	KHSRP
Description		heterogeneous nuclear ribonucleoprotein H1	KH-type splicing regulatory protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Exosome (RNase Complex) Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	RNA Binding Protein Binding Poly(U) RNA Binding Identical Protein Binding	DNA Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of RNA Splicing	RNA Splicing, Via Transesterification Reactions Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Gene Expression MiRNA Metabolic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of MRNA Stability Negative Regulation Of Nitric Oxide Biosynthetic Process MRNA Transport Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Cellular Response To Cytokine Stimulus
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	ATF4 activates genes in response to endoplasmic reticulum stress KSRP (KHSRP) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs		Copper	Resveratrol Artenimol
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		132 interacting genes: APBB1 ARHGEF16 CATSPER1 CCDC120 CCNK CRMP1 DDX17 DDX5 DUX4 DZIP3 ENKD1 ERG GPANK1 GPS2 HIPK3 HNRNPF HNRNPH3 HNRNPM KHSRP KRTAP13-2 LMO1 LMO3 LNX1 MAGED1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MRPL53 MSI2 MTNR1A MYPOP NCBP1 NCBP2 NDRG1 NFKBID NUDT16L1 OXER1 PATZ1 PCAT1 PEX5 PIN1 POLR1C PPP1R32 RALY RAMAC RBFOX2 RBM38 RNF4 SF1 SF3B4 SNRPB SNRPC SPG21 SREK1 SUMO2 SUMO4 TCERG1 TEKT3 TEKT4 TOM1L1 YPEL3 YWHAG YWHAQ	14 interacting genes: A1CF APBB1 BACE1 EXOSC2 EXOSC3 GADD45A GSK3B HNRNPA1 HNRNPH1 KLHL12 PARN PTBP2 STK3 UBE2I
Entrez ID		3187	8570
HPRD ID		03021	10350
Ensembl ID		ENSG00000169045	ENSG00000088247
Uniprot IDs		A0A384MEJ3 P31943	Q92945
PDB IDs		2LXU 6DHS	2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T
Enriched GO Terms of Interacting Partners?
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