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HNRNPA1 and PRMT1
Data Source:
HPRD
(in vivo, in vitro)
HNRNPA1
PRMT1
Description
heterogeneous nuclear ribonucleoprotein A1
protein arginine methyltransferase 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Membrane
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Methylosome
Molecular Function
Single-stranded DNA Binding
RNA Binding
Single-stranded RNA Binding
Protein Binding
Protein Domain Specific Binding
MiRNA Binding
Pre-mRNA Binding
Telomeric Repeat-containing RNA Binding
G-rich Strand Telomeric DNA Binding
RNA Binding
Protein Binding
Methyltransferase Activity
N-methyltransferase Activity
Protein Methyltransferase Activity
Methyl-CpG Binding
Protein-arginine N-methyltransferase Activity
Enzyme Binding
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Histone Methyltransferase Activity
Identical Protein Binding
Histone Methyltransferase Activity (H4-R3 Specific)
Mitogen-activated Protein Kinase P38 Binding
S-adenosyl-L-methionine Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
Fibroblast Growth Factor Receptor Signaling Pathway
Viral Process
RNA Metabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Cellular Response To Glucose Starvation
MRNA Transport
Nuclear Export
Import Into Nucleus
Cellular Response To Sodium Arsenite
In Utero Embryonic Development
Protein Methylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Histone Methylation
Peptidyl-arginine Methylation
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Neuron Projection Development
Histone H4-R3 Methylation
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Hemoglobin Biosynthetic Process
Protein Homooligomerization
Positive Regulation Of P38MAPK Cascade
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
RMTs methylate histone arginines
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Extra-nuclear estrogen signaling
Estrogen-dependent gene expression
Drugs
S-adenosyl-L-homocysteine
Diseases
GWAS
Meat-related diet (
32066663
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Schizophrenia (
29483656
)
Interacting Genes
114 interacting genes:
ABHD16A
APP
BCL2L1
CLK1
ERG
ESR1
FEN1
H3-4
H3C1
HIPK3
HMGA1
HNRNPH3
KHSRP
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NFKBIA
NR0B2
NR3C1
PABPN1
PHYHIP
PPIL1
PRKDC
PRMT1
PRMT2
PRMT3
PRRC2A
PTEN
RNF14
RPL21
RPS6KB2
SAFB
SNRNP200
SREK1
SRPK1
SRPK2
SUFU
TFEC
TNPO1
TRA2B
TRAF6
TSHR
TTF2
XIAP
XRN1
151 interacting genes:
AR
ARPC3
ASH2L
AXIN1
BRCA1
BTG1
BTG2
C4orf17
CAPRIN1
CDC37
CEP162
CIRBP
CNOT8
COIL
DAXX
DCAF16
DCAF8
DHX9
EIF4A1
EP300
ESR1
EWSR1
FAM83D
FAM9A
FBL
FBXL17
FBXO7
FGF2
FLII
FUS
GLI1
GPATCH2L
GRHL3
GRIP1
H3C1
H4-16
H4C14
HABP4
HNF4A
HNRNPA1
HNRNPK
HNRNPR
HNRNPU
HNRNPUL1
HROB
IDH3B
IFNAR1
IGSF21
ILF3
KHDRBS1
KHDRBS2
KHDRBS3
LRIF1
MBP
MECOM
MED31
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR138-1
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR34A
MIR34C
MIR363
MIR451A
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MLST8
NCOA1
NCOA2
NCOA3
NOL4
NRIP1
NTAQ1
OFCC1
PPARA
PRMT8
QKI
RBM15
RELA
RNF187
RUNX1
S100A8
SAMD3
SHLD1
SIRT1
SPAG8
SPEG
SPSB1
SPSB2
STAT1
STAT5A
STUB1
SUPT5H
TBX6
TERF2
THRB
TP53
TRIM48
UBE4B
VHL
VPS72
WDFY3
WDR33
YLPM1
YWHAG
ZBTB14
ZMYM5
ZNF451
Entrez ID
3178
3276
HPRD ID
01242
04257
Ensembl ID
ENSG00000135486
ENSG00000126457
Uniprot IDs
A0A024RAZ7
A0A024RB53
P09651
Q99873
PDB IDs
1HA1
1L3K
1PGZ
1PO6
1U1K
1U1L
1U1M
1U1N
1U1O
1U1P
1U1Q
1U1R
1UP1
2H4M
2LYV
2UP1
4YOE
5MPG
5MPL
5ZGD
5ZGL
6BXX
6DCL
6J60
6NT2
Enriched GO Terms of Interacting Partners
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