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NR4A1 and BCL2L10
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
NR4A1
BCL2L10
Description
nuclear receptor subfamily 4 group A member 1
BCL2 like 10
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Mitochondrion
Cytosol
Nuclear Membrane
Mitochondrion
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Cytosol
Membrane
Integral Component Of Membrane
Nuclear Membrane
Mitochondria-associated Endoplasmic Reticulum Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Nuclear Receptor Activity
Protein Binding
Zinc Ion Binding
Glucocorticoid Receptor Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Caspase Binding
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Intracellular Receptor Signaling Pathway
Endothelial Cell Chemotaxis
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Fat Cell Differentiation
Negative Regulation Of Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Type B Pancreatic Cell Proliferation
Cellular Response To Corticotropin-releasing Hormone Stimulus
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Spermatogenesis
Female Gamete Generation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Apoptotic Process
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
AKT phosphorylates targets in the nucleus
Nuclear Receptor transcription pathway
Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases
GWAS
Interacting Genes
87 interacting genes:
ABCA5
ABCB11
ABCC13
ABCC6
ABCG8
AKT1
ANKIB1
ARHGEF10L
ARHGEF5
ATM
ATXN1
BBS10
BCL2
BCL2A1
BCL2L10
CD2AP
CDKN2D
CHD1L
CHD3
CHEK2
CPT1A
CUTA
DIABLO
EP300
FAF1
FXYD3
GADD45GIP1
GK
GLOD4
GLUD1
HADHA
HES1
HIF1A
HNRNPA2B1
HSP90AB1
KAT2B
KRTAP10-1
KRTAP10-5
LONRF1
LSS
MAP3K1
MAPK1
MAPK8
MED1
MED31
NACAD
NCOA1
NCOA2
NCOA3
NCOR2
NDRG1
NFKB1
NR3C1
PGBD1
PML
POLA2
PPARG
PPBP
PPM1A
PRDX4
PRDX6
RBL1
ROBO2
RPL7
RPS6KA1
RPS6KA3
RPS6KA5
RPS6KA6
RTN4
RXRA
RXRG
SERPINA4
SERPING1
SMAD3
SOCS4
STAT3
SUGT1
TCF4
TP53
TRAF2
TRIM28
TUBB4A
VASP
VHL
YWHAZ
ZNF331
ZNF579
15 interacting genes:
APAF1
BAD
BAK1
BAX
BCL2
BCL2L1
BCL2L11
BECN1
BIK
BMF
CASP8
MGST2
NR4A1
SAMD4B
TMEM200A
Entrez ID
3164
10017
HPRD ID
00744
06071
Ensembl ID
ENSG00000123358
ENSG00000137875
Uniprot IDs
A0A024R126
F5GXF0
P22736
Q6ZMM6
H0YMD5
Q9HD36
PDB IDs
2QW4
3V3E
3V3Q
4JGV
4KZI
4KZJ
4KZM
4RE8
4REE
4REF
4RZE
4RZF
4RZG
4WHF
4WHG
6KZ5
6LC1
4B4S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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