Wiki-Pi
About
Search
Browse
People
Updates
Search
UBE2K and MID1
Data Source:
BioGRID
(two hybrid, two hybrid)
UBE2K
MID1
Description
ubiquitin conjugating enzyme E2 K
midline 1
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Filopodium Tip
Spindle
Cytosol
Microtubule
Microtubule Associated Complex
Cytoplasmic Microtubule
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Microtubule Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Homodimerization Activity
Phosphoprotein Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Peptidyl-threonine Phosphorylation
Free Ubiquitin Chain Polymerization
Protein Ubiquitination
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Interferon-beta
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Protein K48-linked Ubiquitination
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Microtubule Cytoskeleton Organization
Pattern Specification Process
Positive Regulation Of Stress-activated MAPK Cascade
Protein Localization To Microtubule
Interferon-gamma-mediated Signaling Pathway
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Negative regulators of DDX58/IFIH1 signaling
Antigen processing: Ubiquitination & Proteasome degradation
Interferon gamma signaling
Drugs
Diseases
Opitz-GBBB syndrome
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Plasma amyloid beta peptide concentrations (ABx-40) (
24535457
)
Platelet count (
32888494
)
Interacting Genes
95 interacting genes:
AMFR
ANAPC11
BARD1
BFAR
BIRC7
BIRC8
BRCA1
CASP12
CBLC
CCNC
CDC6
DDI1
DDX58
DIABLO
DTX3
DTX3L
DZIP3
EXOSC7
FZR1
HTT
ITCH
ITSN1
KRIT1
LRSAM1
MAP3K1
MARCHF3
MARCHF7
MDM2
MEOX2
MID1
MID2
MIPOL1
MKRN2
MKRN3
NEDD4L
NEDD8
NFKB1
NUB1
PAX6
PIAS4
PICK1
PJA1
PRKN
PRPF40A
PRRG4
RBCK1
RC3H2
REL
RING1
RLIM
RNF111
RNF114
RNF125
RNF138
RNF144A
RNF166
RNF167
RNF182
RNF183
RNF185
RNF2
RNF31
RNF32
RNF4
RNF41
RNF5
SDCBP
SENP1
SH3RF1
SIAH1
SMURF1
TP53
TRAF7
TRAIP
TRIM2
TRIM27
TRIM3
TRIM31
TRIM34
TRIM35
TRIM39
TRIM43
TRIM5
TRIM50
TRIM63
TSN
UBA1
UBB
UBE2I
UBOX5
UHRF2
USP1
WWP2
ZDHHC17
ZNF384
44 interacting genes:
BYSL
CDC37
CRY2
DYRK4
EHHADH
ELOA
EPN2
EPN3
FAM50B
FKBP1A
GMCL1
HMG20B
HTT
IGBP1
KIF9
MEOX1
MID1IP1
MID2
N4BP1
OTUB2
PAX6
PKN1
PPP2CA
PPP2CB
PTCD2
PTPA
SPAG5
STK36
TCEANC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2K
UBE2L3
UBE2L6
UBE2N
UBE2V1
UBE2W
UBTD1
ZNF618
Entrez ID
3093
4281
HPRD ID
04165
02047
Ensembl ID
ENSG00000078140
ENSG00000101871
Uniprot IDs
B3KSH4
B4DIZ2
P61086
A0A024RBV4
A0A087X0X0
A0A087X255
O15344
PDB IDs
1YLA
2O25
3E46
3F92
3K9O
3K9P
5DFL
6IF1
6JB6
6JB7
2DQ5
2FFW
2JUN
5IM8
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?