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ANXA1 and YWHAQ
Data Source:
BioGRID
(pull down)
ANXA1
YWHAQ
Description
annexin A1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Image
GO Annotations
Cellular Component
Cornified Envelope
Phagocytic Cup
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Actin Filament
Plasma Membrane
Adherens Junction
Focal Adhesion
Cell Surface
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Extrinsic Component Of Membrane
Cytoplasmic Vesicle Membrane
Extrinsic Component Of External Side Of Plasma Membrane
Extrinsic Component Of Endosome Membrane
Motile Cilium
Early Endosome Membrane
Mitochondrial Membrane
Vesicle
Protein-containing Complex
Sarcolemma
Mast Cell Granule
Collagen-containing Extracellular Matrix
Extracellular Exosome
Synaptic Membrane
Cytoplasm
Mitochondrion
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Molecular Function
Single-stranded DNA Binding
Single-stranded RNA Binding
Signaling Receptor Binding
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipid Binding
Phospholipase A2 Inhibitor Activity
Double-stranded DNA Helicase Activity
Identical Protein Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
DNA/DNA Annealing Activity
Protein Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Identical Protein Binding
Ion Channel Binding
Protein N-terminus Binding
14-3-3 Protein Binding
Biological Process
Neutrophil Homeostasis
Adaptive Immune Response
Monocyte Chemotaxis
Regulation Of Leukocyte Migration
Phagocytosis
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Cell Shape
Response To X-ray
Myoblast Migration Involved In Skeletal Muscle Regeneration
Peptide Cross-linking
Cytokine-mediated Signaling Pathway
Insulin Secretion
Keratinocyte Differentiation
Prostate Gland Development
Endocrine Pancreas Development
Positive Regulation Of Vesicle Fusion
Positive Regulation Of Prostaglandin Biosynthetic Process
Actin Cytoskeleton Reorganization
Response To Estradiol
DNA Duplex Unwinding
Regulation Of Interleukin-1 Production
Negative Regulation Of Interleukin-8 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Neutrophil Apoptotic Process
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Gliogenesis
Positive Regulation Of T Cell Proliferation
Response To Drug
Negative Regulation Of Apoptotic Process
Response To Peptide Hormone
Estrous Cycle
Innate Immune Response
Positive Regulation Of T-helper 1 Cell Differentiation
Negative Regulation Of T-helper 2 Cell Differentiation
Negative Regulation Of Exocytosis
Alpha-beta T Cell Differentiation
Regulation Of Hormone Secretion
Arachidonic Acid Secretion
Negative Regulation Of Protein Secretion
Regulation Of Inflammatory Response
Cellular Response To Hydrogen Peroxide
Hepatocyte Differentiation
Prolactin Secretion
Response To Interleukin-1
Cellular Response To Glucocorticoid Stimulus
Granulocyte Chemotaxis
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Wound Healing
Neutrophil Clearance
Cell-cell Adhesion
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Phospholipase A2 Activity
Protein Targeting
Small GTPase Mediated Signal Transduction
Substantia Nigra Development
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transcription, DNA-templated
Membrane Organization
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
Smooth Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Drugs
Amcinonide
Fluocinolone acetonide
Hydrocortisone
Methylprednisolone
Clobetasol propionate
Budesonide
Dexamethasone
Hydrocortisone aceponate
Hydrocortisone acetate
Hydrocortisone butyrate
Hydrocortisone cypionate
Hydrocortisone phosphate
Hydrocortisone probutate
Hydrocortisone valerate
Prednisolone phosphate
Dexamethasone acetate
Betamethasone phosphate
Phenethyl Isothiocyanate
Diseases
GWAS
Blood protein levels (
28240269
)
Chronotype (
30696823
)
Metabolite levels (
23823483
)
Parkinson's disease (
26227905
)
Schizophrenia, bipolar disorder and depression (combined) (
20713499
)
Urate levels in obese individuals (
25811787
)
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
34 interacting genes:
APBB1
CCT7
COPS6
CSAD
CZIB
DYSF
EGFR
ERG28
FAF1
FPR1
GAPDH
HMGA1
HSPB1
KLHL23
KMT2B
KRT8
LNPK
LRIF1
MEIS2
OTUB1
PRKCI
RPA1
S100A11
SRC
SUMO2
TGM2
TRPM7
UBE2D1
UBE2I
UBE3A
UCHL5
UNC119
USP7
YWHAQ
240 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
APC
AR
ARHGAP10
ARHGEF16
ARHGEF2
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDK17
CDK18
CDKN1A
CDKN1B
CEP170
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
EXO1
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC4
HDAC5
HDAC7
HNRNPC
HNRNPF
HNRNPH1
HNRNPK
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
IQGAP1
IRS2
ITGB4
ITPRID2
KANK1
KCNK15
KCNK3
KCNK9
KIF1C
KIF23
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LMO7
LYST
MAGOH
MAP3K3
MAP3K5
MARK2
MARK3
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PAK4
PANK1
PCM1
PDCD6
PDE3A
PDE3B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C2B
PIK3C3
PIK3CB
PKM
PPFIBP1
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
PTPN3
RAF1
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TP53BP2
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBE2L3
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR61
WDR77
WEE1
WTAP
WWC2
WWP1
YAP1
YWHAE
YWHAG
ZC3H13
ZHX2
Entrez ID
301
10971
HPRD ID
01060
00886
Ensembl ID
ENSG00000135046
ENSG00000134308
Uniprot IDs
P04083
Q5TZZ9
P27348
PDB IDs
1AIN
1BO9
1QLS
5VFW
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
Enriched GO Terms of Interacting Partners
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