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TLX3 and SNTA1
Data Source:
BioGRID
(unspecified method)
TLX3
SNTA1
Description
T cell leukemia homeobox 3
syntrophin alpha 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Intracellular Anatomical Structure
Cytoplasm
Cytoskeleton
Dystrophin-associated Glycoprotein Complex
Syntrophin Complex
Lateral Plasma Membrane
Neuromuscular Junction
Protein-containing Complex
Sarcolemma
Synapse
Postsynaptic Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Actin Binding
Structural Molecule Activity
Protein Binding
Calmodulin Binding
Sodium Channel Regulator Activity
PDZ Domain Binding
Ion Channel Binding
Nitric-oxide Synthase Binding
ATPase Binding
Biological Process
Neuron Migration
Regulation Of Respiratory Gaseous Exchange By Nervous System Process
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Respiratory Gaseous Exchange By Respiratory System
Negative Regulation Of Neuron Differentiation
Animal Organ Development
Neuron Fate Specification
Regulation Of Heart Rate
Regulation Of Vasoconstriction By Circulating Norepinephrine
Muscle Contraction
Neuromuscular Junction Development
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Ventricular Cardiac Muscle Cell Action Potential
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Regulation Of Sodium Ion Transmembrane Transport
Pathways
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Body size at age 10 (
32376654
)
HDL cholesterol x physical activity interaction (1df test) (
30670697
)
HDL cholesterol x physical activity interaction (2df test) (
30670697
)
Interacting Genes
106 interacting genes:
ACY1
AKAP9
ANKRD10
ANKRD33
AOC1
APBB1IP
ARMC5
ASB12
ATP6V0D1
B9D2
BPIFA1
C11orf1
C11orf45
C19orf54
C2orf42
CEACAM6
CRX
CSNK2B
CTNNA3
DENND4A
EFEMP2
ERAS
FAM166B
FAM168B
FCSK
FNTB
FOSB
FOXH1
GGTLC2
GOLGA6L9
GTF2A1L
H2BC11
HNRNPUL1
HOPX
HSPB2
HSPB2-C11orf52
HYI
IGFL2
ING4
INTS11
IRF9
ITIH6
KRT34
KRTAP11-1
KRTAP13-3
KRTAP19-1
KRTAP19-7
KRTAP3-1
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
LASP1
LMO2
MAGED1
MEIS1
METTL27
MORN5
MSX2
NDUFAB1
NHLRC4
NICN1
OIP5
PLA2G10
PLAAT1
POU2AF1
POU6F2
PPP1CC
PQBP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMB11
REL
ROR2
RSKR
SERPINE1
SLC15A2
SMU1
SNTA1
SP1
SPATA46
SPRYD7
STH
SYNGAP1
TBX22
TCIRG1
TEKT5
TEX37
THTPA
TLE1
TLE2
TMEM42
TOX2
TP53BP1
TRIM42
UFSP1
WDR83
YPEL3
ZBTB32
ZNF34
ZNF41
ZNF44
74 interacting genes:
ABCA1
ABCC4
ACTA2
ADAMTS6
ADGRB1
ADGRB2
ADGRB3
ADH5
ADRA1D
ADRA2A
ADRB1
AGTR2
ATP2B2
ATP6V0B
C3AR1
CALM1
CD3E
CNKSR2
COPB1
DGKZ
DMD
DTNA
DTNB
F8A1
FABP1
FAM189B
GDA
GLS
GLS2
GOLGA2
GRB2
GUCY1A2
HTR2B
HTR2C
IL2RA
IL9
ITGB5
KCNA4
KCNA5
KCNJ10
KCNJ12
KCNJ15
KCNJ4
KIF1B
LMO1
MAP4
MAPK12
MAS1
MAST1
MCM7
MED8
MTMR2
NAT1
NMU
NOS1
PFN2
PRLHR
PSKH1
RPS6KA1
SCN1A
SCN4A
SCN5A
SCTR
SLC16A7
SLC1A7
SLC2A3
SLC6A3
SSTR1
TGFA
TLX3
TRA
TRBV12-3
UTRN
XRCC6
Entrez ID
30012
6640
HPRD ID
06868
03009
Ensembl ID
ENSG00000164438
ENSG00000101400
Uniprot IDs
O43711
Q13424
PDB IDs
Enriched GO Terms of Interacting Partners
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