PILRB and SAMSN1

Data Source:
HPRD (in vitro)

		PILRB	SAMSN1
Description		paired immunoglobin like type 2 receptor beta	SAM domain, SH3 domain and nuclear localization signals 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Ruffle Nucleus Cytoplasm
	Molecular Function	Protein Binding MHC Class I Protein Binding	Phosphotyrosine Residue Binding RNA Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Immune Response	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hemoglobin ( 32888494) Post bronchodilator FEV1 ( 26634245) Subcortical volume (MOSTest) ( 32665545)	Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		6 interacting genes: ABHD16A BRCA1 LYN PTPN11 PTPN6 SAMSN1	10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		29990	64092
HPRD ID		08382	06413
Ensembl ID		ENSG00000121716	ENSG00000155307
Uniprot IDs		Q9UKJ0	Q9NSI8 S6FRS6
PDB IDs		4NFC 4NFD	6UZJ
Enriched GO Terms of Interacting Partners?
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