GMPPB and TXNDC5

Data Source:
BioGRID (two hybrid)

		GMPPB	TXNDC5
Description		GDP-mannose pyrophosphorylase B	thioredoxin domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Mannose-1-phosphate Guanylyltransferase Activity Protein Binding GTP Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	GDP-mannose Biosynthetic Process	Protein Phosphopantetheinylation Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance Neutrophil Degranulation
Pathways		Synthesis of GDP-mannose	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 27798624) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)	Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)
Interacting Genes		5 interacting genes: DPPA4 GLYCTK GMPPA POLR1C TXNDC5	27 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2
Entrez ID		29925	81567
HPRD ID		13589	18249
Ensembl ID		ENSG00000173540	ENSG00000239264
Uniprot IDs		Q9Y5P6	A0A024QZV0 Q8NBS9
PDB IDs			2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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