TFPT and PAWR

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		TFPT	PAWR
Description		TCF3 fusion partner	pro-apoptotic WT1 regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ino80 Complex	Chromatin Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton
	Molecular Function	DNA Binding Protein Binding	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding
	Biological Process	DNA Repair DNA Recombination Protein Deubiquitination Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Positive Regulation Of Gene Expression Negative Regulation Of B Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Cellular Senescence
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		32 interacting genes: APP C19orf25 C4orf46 CCDC57 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL ENTR1 HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 PIN1 PSMB1 RALBP1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM2 TPM3 TRAF1	16 interacting genes: AATF ATP5F1C DAPK3 DRD2 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1
Entrez ID		29844	5074
HPRD ID		10266	09051
Ensembl ID		ENSG00000105619	ENSG00000177425
Uniprot IDs		A0A024R4Q5 P0C1Z6	Q96IZ0
PDB IDs			2JK9
Enriched GO Terms of Interacting Partners?
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