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PACSIN3 and SMARCD1
Data Source:
BioGRID
(two hybrid)
PACSIN3
SMARCD1
Description
protein kinase C and casein kinase substrate in neurons 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Cytosol
Cytoskeleton
Plasma Membrane
Extracellular Exosome
Nucleus
Nucleoplasm
SWI/SNF Complex
Intracellular Membrane-bounded Organelle
NpBAF Complex
NBAF Complex
Molecular Function
Protein Binding
Phospholipid Binding
Cytoskeletal Protein Binding
Lipid Binding
Calcium Channel Inhibitor Activity
Identical Protein Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Transcription Coactivator Activity
Signaling Receptor Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
Endocytosis
Cytoskeleton Organization
Regulation Of Endocytosis
Negative Regulation Of Endocytosis
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Calcium Ion Transport
Plasma Membrane Tubulation
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Transcription By RNA Polymerase II
Chromatin-mediated Maintenance Of Transcription
Cellular Response To Fatty Acid
Pathways
Clathrin-mediated endocytosis
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Waist-to-hip ratio adjusted for body mass index (
26785701
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Interacting Genes
23 interacting genes:
ADAM12
ADAM15
ASAP1
ASAP2
ATXN7L2
CLNK
DNM1
ITSN1
KRTAP12-2
LGALS13
PACSIN1
PACSIN2
PAK2
RAF1
SMARCD1
SOS1
SOS2
SPRY2
SYNJ1
TERF2IP
TNPO2
TRPV4
WASL
156 interacting genes:
ABI1
ABI2
ABI3
ADAT2
ANKRD23
ANKRD49
ANKS1A
ANP32B
APOA5
AR
ARMC10
ARRDC3
BCAS2
BEND5
BEX3
BHLHB9
BLOC1S5
BRWD1
C19orf54
C1orf109
C4BPA
CALCOCO2
CCDC102B
CCDC130
CCDC197
CCDC33
CCDC85B
CDC5L
CDR2
CDSN
CDX2
CEACAM6
CHFR
CHN2
CLNK
COG6
COL1A2
CORO1A
CUEDC1
CYSRT1
DCTN2
DISC1
EGFL7
EIF4G1
ESR1
ESS2
FAM136A
FAM161A
FBXO7
FEZ1
FOS
FUS
GATA1
GCC1
GIGYF1
GINS3
GOLGA6L9
GRAMD4
HES6
HNRNPC
HOMEZ
HOXD3
HSF2BP
HSPB1
IGKC
IKBIP
IKZF3
INSC
IQCB1
JUN
KATNBL1
KDM1A
KEAP1
KIAA0753
KLF1
KMT5B
KRT15
KRT16
KRT18
KRT27
KRT31
KRT34
KRT37
KRT38
KRT75
LDB2
LDOC1
LZTS2
MAGEA2
MAGEA2B
MAGEA6
MED4
MKRN3
MTNR1B
MTUS2
NAB2
NECAB2
NELFA
NME1
NONO
NR1H4
NR3C1
NUCB2
NUDT16L1
NUTM1
PACSIN3
PAICS
PBX4
PCBD1
PGR
PICK1
PIH1D1
PKNOX2
PLAGL2
PPM1J
PRDX1
PRMT6
PSTPIP1
RIF1
RORB
RPS29
SCARA5
SCHIP1
SCNM1
SERTAD3
SHISA6
SMARCB1
SMUG1
SNF8
SPSB2
STH
STMN3
SYCE1L
TCP10L
THOC7
TLE5
TNIP2
TP53
TRIM27
TRIM54
TRIM72
USHBP1
USP54
VPS37B
WASHC1
WWP2
YWHAG
ZC2HC1C
ZMAT5
ZMYND12
ZNF417
ZNF438
ZNF511
ZNF629
ZNF655
ZNF69
Entrez ID
29763
6602
HPRD ID
05937
03438
Ensembl ID
ENSG00000165912
ENSG00000066117
Uniprot IDs
Q9UKS6
Q96GM5
PDB IDs
6LTH
6LTJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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