RANGRF and RANBP1

Data Source:
HPRD (in vitro)

		RANGRF	RANBP1
Description		RAN guanine nucleotide release factor	RAN binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Rough Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Intercalated Disc Perinuclear Region Of Cytoplasm	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Centrosome Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Sodium Channel Regulator Activity Small GTPase Binding Ion Channel Binding	GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Cadherin Binding
	Biological Process	Regulation Of Heart Rate Regulation Of Membrane Depolarization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Exit From Endoplasmic Reticulum Regulation Of Membrane Potential Regulation Of Catalytic Activity Regulation Of Microtubule Nucleation By Ran Protein Signal Transduction Regulation Of Bundle Of His Cell Action Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Regulation Of Sodium Ion Transmembrane Transporter Activity	Signal Transduction Viral Process Positive Regulation Of GTPase Activity Positive Regulation Of Mitotic Centrosome Separation Intracellular Transport
Pathways		Phase 0 - rapid depolarisation	Rev-mediated nuclear export of HIV RNA
Drugs			Copper Phenethyl Isothiocyanate
Diseases
GWAS
Interacting Genes		4 interacting genes: PTPN11 RAN RANBP1 ZDHHC17	7 interacting genes: CD93 KPNB1 MDM2 NUPR1 RAN RANGRF RCC1
Entrez ID		29098	5902
HPRD ID		06407	03110
Ensembl ID		ENSG00000108961	ENSG00000099901
Uniprot IDs		Q9HD47	A0A140VK94 B3KUP2 B4DE76 D3DX26 F6WQW2 P43487
PDB IDs		5YFG	1K5D 1K5G
Enriched GO Terms of Interacting Partners?
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