BABAM1 and BABAM2

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (two hybrid)

		BABAM1	BABAM2
Description		BRISC and BRCA1 A complex member 1	BRISC and BRCA1 A complex member 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body BRCA1-A Complex BRISC Complex	Nuclear Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex
	Molecular Function	Protein Binding	Peroxisome Targeting Sequence Binding Tumor Necrosis Factor Receptor Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization Cell Cycle Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization Apoptotic Process Cellular Response To DNA Damage Stimulus Cell Cycle Signal Transduction Response To Ionizing Radiation Protein Deubiquitination Negative Regulation Of Apoptotic Process Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Epithelial ovarian cancer ( 25581431) Mitochondrial DNA copy number ( 30704525)	Blond vs. brown/black hair color ( 30531825) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Urate levels ( 31578528) Uterine fibroids ( 31649266)
Interacting Genes		8 interacting genes: AKT1 BABAM2 BRCA1 SHMT2 TERF2IP TNKS TRIM27 UBC	7 interacting genes: BABAM1 GFI1B NCOA3 SHMT2 SUMO2 UBC UBE2D1
Entrez ID		29086	9577
HPRD ID		13702	08498
Ensembl ID		ENSG00000105393	ENSG00000158019
Uniprot IDs		A0A024R7L2 J3KQS6 Q9NWV8	Q9NXR7
PDB IDs		6H3C	6H3C 6R8F
Enriched GO Terms of Interacting Partners?
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