RELL2 and FAM3C

Data Source:
BioGRID (two hybrid)

		RELL2	FAM3C
Description		RELT like 2	FAM3 metabolism regulating signaling molecule C
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Collagen Binding	Cytokine Activity Protein Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of P38MAPK Cascade	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)
Interacting Genes		21 interacting genes: ANKRD46 ASPH CDIPT CLDND2 COL4A5 FAM3C LPAR3 MIP NSG1 OXSR1 PLP1 RELL1 RTP2 SEC22B SLC30A8 SLC35A1 SMIM1 TFRC TSPAN33 TSPO2 ZFPL1	48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		285613	10447
HPRD ID		12830	12270
Ensembl ID		ENSG00000164620	ENSG00000196937
Uniprot IDs		Q8NC24	Q92520
PDB IDs			5LC2
Enriched GO Terms of Interacting Partners?
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