SLC26A11 and C5AR2

Data Source:
BioGRID (two hybrid)

		SLC26A11	C5AR2
Description		solute carrier family 26 member 11	complement component 5a receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell
	Molecular Function	Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Anion Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Ion Transport Sulfate Transport Sulfate Transmembrane Transport	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis
Pathways		Multifunctional anion exchangers	Peptide ligand-binding receptors Regulation of Complement cascade
Drugs
Diseases
GWAS		Interleukin-1-receptor antagonist levels ( 22205395) Ischemic stroke ( 26732560)
Interacting Genes		2 interacting genes: C5AR2 SMIM1	17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234
Entrez ID		284129	27202
HPRD ID		11569	17072
Ensembl ID		ENSG00000181045	ENSG00000134830
Uniprot IDs		Q86WA9	Q9P296
PDB IDs
Enriched GO Terms of Interacting Partners?
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