CCR10 and CCL7

Data Source:
HPRD (in vivo)

		CCR10	CCL7
Description		C-C motif chemokine receptor 10	C-C motif chemokine ligand 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Binding Chemokine Activity Heparin Binding CCR1 Chemokine Receptor Binding CCR2 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Monocyte Chemotaxis Cellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Cytoskeleton Organization Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Regulation Of Cell Shape Response To Gamma Radiation Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Ethanol Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Crohn's disease ( 28067908 22412388 21102463) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908)
Interacting Genes		10 interacting genes: ARPC3 CCL19 CCL2 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A	18 interacting genes: ACKR1 ACKR2 ACKR4 CCR1 CCR10 CCR3 CCR5 CXCL6 FEZ1 MMP1 MMP13 MMP14 MMP2 MMP3 TLE5 UBQLN1 UBQLN2 XCL2
Entrez ID		2826	6354
HPRD ID		02586	01150
Ensembl ID		ENSG00000184451	ENSG00000108688
Uniprot IDs		P46092	P80098
PDB IDs			1BO0 1NCV 4ZKC
Enriched GO Terms of Interacting Partners?
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