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GNG5 and GNB4
Data Source:
BioGRID
(pull down)
HPRD
(two hybrid)
GNG5
GNB4
Description
G protein subunit gamma 5
G protein subunit beta 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
G-protein Beta/gamma-subunit Complex
Extracellular Exosome
Cytoplasm
Lysosomal Membrane
Cytosol
Heterotrimeric G-protein Complex
Extracellular Exosome
Molecular Function
GTPase Activity
Protein Binding
PDZ Domain Binding
G-protein Beta-subunit Binding
Protein Binding
G-protein Gamma-subunit Binding
Protein-containing Complex Binding
Biological Process
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Substantia Nigra Development
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
29892015
)
Heart rate (
23583979
)
Resting heart rate (
29769521
27798624
)
Interacting Genes
12 interacting genes:
AMOTL2
EPS15L1
GNB1
GNB2
GNB3
GNB4
GNB5
GOLGA2
KRT31
KRT40
MDFI
TRAF1
18 interacting genes:
GNAI1
GNAI2
GNAI3
GNG10
GNG11
GNG12
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNG8
GNGT1
GNGT2
MTNR1A
MTNR1B
PTEN
Entrez ID
2787
59345
HPRD ID
11865
09973
Ensembl ID
ENSG00000174021
ENSG00000114450
Uniprot IDs
P63218
Q9HAV0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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