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GNAZ and DRD5
Data Source:
HPRD
(in vivo, in vitro)
GNAZ
DRD5
Description
G protein subunit alpha z
dopamine receptor D5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Cilium
Brush Border Membrane
Synapse
Ciliary Membrane
Non-motile Cilium
Molecular Function
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
G Protein-coupled Serotonin Receptor Binding
Metal Ion Binding
Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs
G Protein-coupled Receptor Activity
Dopamine Neurotransmitter Receptor Activity
Protein Binding
Dopamine Binding
Biological Process
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Synaptic Transmission, Dopaminergic
Response To Amphetamine
Regulation Of Systemic Arterial Blood Pressure By Vasopressin
Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure
Cellular Calcium Ion Homeostasis
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Adenylate Cyclase Activity
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Dopamine Receptor Signaling Pathway
Chemical Synaptic Transmission
Associative Learning
Transmission Of Nerve Impulse
Negative Regulation Of NAD(P)H Oxidase Activity
Wound Healing
Response To Cocaine
Positive Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Blood Pressure
Regulation Of Female Receptivity
Sensitization
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Long-term Synaptic Depression
Cellular Response To Catecholamine Stimulus
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Reactive Oxygen Species Metabolic Process
Pathways
PLC beta mediated events
PLC beta mediated events
G-protein activation
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
G alpha (z) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
ADORA2B mediated anti-inflammatory cytokines production
Dopamine receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Ziprasidone
Cabergoline
Cabergoline
Olanzapine
Olanzapine
Loxapine
Loxapine
Imipramine
Chlorpromazine
Chlorpromazine
Lamotrigine
Cinnarizine
Lisuride
Ergotamine
Apomorphine
Paroxetine
Trimipramine
Fenoldopam
Dopamine
Dopamine
Carphenazine
Ergoloid mesylate
Pergolide
Bromocriptine
Quetiapine
Levodopa
Aripiprazole
Methotrimeprazine
Zuclopenthixol
Rotigotine
Mianserin
Quinagolide
Zotepine
Dihydro-alpha-ergocryptine
Epicriptine
Pipradrol
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Handedness (Left-handed vs. non-left-handed) (
31504236
)
Handedness (left-handed vs. right-handed) (
31504236
)
Height (
18391951
)
Processed meat consumption (
32066663
)
Gut microbiota (bacterial taxa) (
27723756
)
Impulsivity (motor) (
30718321
)
Lung cancer (
28604730
)
Manganese levels (
26025379
)
Metabolite levels (
23823483
)
Interacting Genes
16 interacting genes:
ADORA1
APP
DRD2
DRD5
EYA1
EYA2
LRRK1
NMT1
NUCB1
OPRD1
PRKCD
RAP1GAP
RGS10
RGS19
RGS20
RGS7
7 interacting genes:
GABRG2
GNA12
GNA13
GNAZ
NBPF19
NCS1
NOTCH2NLA
Entrez ID
2781
1816
HPRD ID
00746
00542
Ensembl ID
ENSG00000128266
ENSG00000169676
Uniprot IDs
P19086
Q8IY73
P21918
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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