SGSM3 and RAB39B

Data Source:
BioGRID (two hybrid)

		SGSM3	RAB39B
Description		small G protein signaling modulator 3	RAB39B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Gap Junction	Golgi Membrane Golgi Apparatus Plasma Membrane Cytoplasmic Vesicle Membrane Vesicle Neuron Projection
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Cell Cycle Arrest Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Catabolic Process Plasma Membrane To Endosome Transport Activation Of GTPase Activity Regulation Of Cilium Assembly	Autophagy Regulation Of Autophagy Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Synapse Organization
Pathways			RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS		Body mass index ( 26426971) Breast size ( 29855537) Chronotype ( 27494321) Height ( 19570815) Mammographic density (dense area) ( 25342443) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		9 interacting genes: CHRM3 FMO3 GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35	6 interacting genes: GOLGA2 RAB3GAP1 RUFY1 SGSM3 VPS26C ZDHHC17
Entrez ID		27352	116442
HPRD ID		15285	06703
Ensembl ID		ENSG00000100359	ENSG00000155961
Uniprot IDs		B4DVE3 B9A6J5 Q96HU1	Q96DA2
PDB IDs			6S5F
Enriched GO Terms of Interacting Partners?
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