EIF3K and EIF3G

Data Source:
HPRD (in vitro)

		EIF3K	EIF3G
Description		eukaryotic translation initiation factor 3 subunit K	eukaryotic translation initiation factor 3 subunit G
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GO Annotations	Cellular Component	Nucleus Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1	28 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA MEOX2 METTL3 MIF4GD MPHOSPH6 PALS2 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14
Entrez ID		27335	8666
HPRD ID		11740	04886
Ensembl ID		ENSG00000178982	ENSG00000130811
Uniprot IDs		K7EK53 K7ERF1 Q9UBQ5 U3LUI4	O75821
PDB IDs		1RZ4 3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09	2CQ0 2MJC 5K0Y 6YBS 6ZMW
Enriched GO Terms of Interacting Partners?
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