LSM3 and SNRPD1

Data Source:
BioGRID (two hybrid)

		LSM3	SNRPD1
Description		LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	small nuclear ribonucleoprotein D1 polypeptide
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Commitment Complex Nucleus Nucleoplasm U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA 3'-end Binding	RNA Binding Protein Binding U1 SnRNP Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Import Into Nucleus
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Offspring birth weight ( 31043758) PR interval ( 32439900) Red blood cell count ( 32888494)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		48 interacting genes: CCND3 CDKN2D CEP95 CLNS1A CNOT7 DDIT4L DLX4 EEF1A1 EIF4EBP2 EXOSC1 EXOSC5 GDF9 GSTA1 HSPB1 INCA1 KEAP1 KLF3 LSM1 LSM10 LSM12 LSM2 LSM5 LSM6 LSM7 LSM8 NACC1 PIAS1 QKI SF3B2 SH3GLB2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPF SNRPG TCL1A TEPSIN TFIP11 THOC5 TRAPPC2 TRAPPC2B UTP14A WDR77 WDR83 XPC XRN2 YBX1	18 interacting genes: CLNS1A DDX20 ERCC6 GEMIN2 GEMIN4 GEMIN5 IL7R LSM3 LSM8 PRMT5 PTEN SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77
Entrez ID		27258	6632
HPRD ID		06283	03040
Ensembl ID		ENSG00000170860	ENSG00000167088
Uniprot IDs		P62310	P62314
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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