SIT1 and MALL

Data Source:
BioGRID (two hybrid)

		SIT1	MALL
Description		signaling threshold regulating transmembrane adaptor 1	mal, T cell differentiation protein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Golgi Membrane Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft
	Molecular Function	Protein Binding Kinase Binding SH2 Domain Binding	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation	Myelination Cholesterol Homeostasis
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes		17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70	68 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35C2 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I ZP3
Entrez ID		27240	7851
HPRD ID		05394	15997
Ensembl ID		ENSG00000137078	ENSG00000144063
Uniprot IDs		Q9Y3P8	Q13021
PDB IDs
Enriched GO Terms of Interacting Partners?
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