CYTH4 and PCM1

Data Source:
BioGRID (two hybrid)

		CYTH4	PCM1
Description		cytohesin 4	pericentriolar material 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Centriolar Satellite Intercellular Bridge	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways		Intra-Golgi traffic	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Uterine fibroids ( 28836065)	Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Triglyceride levels ( 32203549) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		24 interacting genes: AMOTL2 CBY2 CCDC120 CCDC197 CCDC6 CNKSR1 CTAG1A CTAG1B FOS FOSB HOOK2 IPCEF1 KANK2 KIFC3 KRT15 KRT16 KRT34 KRT40 PCM1 PSMB1 SNAPC5 SYCE1L TRIM54 USHBP1	43 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 CYTH4 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FAM81A FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 MCRS1 NDC80 NECAB2 PCNT PRC1 PRKCI RALBP1 RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		27128	5108
HPRD ID		07354	02624
Ensembl ID		ENSG00000100055	ENSG00000078674
Uniprot IDs		B4E2V8 Q9UIA0	A2RUU9 B9EIS5 Q15154
PDB IDs			6HYL 6HYM
Enriched GO Terms of Interacting Partners?
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